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The Specificity of Cervical Facet Medial Branch Blocks

Randomized Study Comparing the Accuracy and Specificity of Cervical Facet Medial Branch Blocks With 0.25 ml and 0.5 ml of Local Anesthetic

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00613340
Enrollment
20
Registered
2008-02-13
Start date
2008-01-31
Completion date
2009-04-30
Last updated
2009-08-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cervical Facet Arthropathy, Neck Pain

Keywords

Cervical pain, Zygapophysial joint, Specificity

Brief summary

Cervical facet arthropathy is a common cause of chronic neck pain. The gold standard for diagnosis is either blocking the facet joints, or more commonly blocking the medial branch nerves that innervate the joints. However, many studies have found a high false-positive rate when the nerves are blocked using 0.5 ml of local anesthetic. We will randomize patients to receive either cervical facet medial branch blocks with 0.25 ml of local anesthetic and contrast, or 0.5 ml. We will then do a CT scan to determine the accuracy and specificity of each block. Our hypothesis is that using the higher volume (0.5 ml) might be responsible for the high false-positive rate.

Detailed description

Inclusion criteria: Dept. of Defense beneficiaries \> 18 years of age; neck pain \> 3 months duration; cervical paraspinal tenderness Exclusion criteria: Radicular signs or symptoms; use of anticoagulants or bleeding disorder. Outcome measures: The number of blocks whereby the contrast bathes the target nerve; the number of blocks whereby the contrast spreads to the medial branch nerve at the adjacent spinal level; the number of times the contrast diffuses into the intervertebral foramen or epidural space. We will also compare pain relief over 8 hours following the block between both volumes.

Interventions

PROCEDURECervical medial branch blocks

Cervical medial branch blocks done with 0.25 ml of local anesthetic and contrast

Sponsors

Army Regional Anesthesia and Pain Management Initiative
CollaboratorFED
Johns Hopkins University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Age \> 18 years * Chronic neck pain \> 3 months * Paraspinal tenderness

Exclusion criteria

* Absence of radicular symptoms * No bleeding diathesis * Contrast allergy

Design outcomes

Primary

MeasureTime frame
Accuracy of injectionsImmediately after nerve blocks.

Secondary

MeasureTime frame
Pain relief after nerve blocks8 hours after blocks

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026