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Youth Substance Use Prevention/Reduction Through Science-based Drug Abuse Education

Youth Substance Use Prevention/Reduction Through Science-based Drug Abuse Education: A High School Pilot Study

Status
Completed
Phases
Phase 1
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00612482
Enrollment
225
Registered
2008-02-11
Start date
2006-12-31
Completion date
2008-01-31
Last updated
2011-03-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Substance Abuse

Keywords

Substance abuse

Brief summary

Our primary goal is to conduct a pilot study of the effects of a new potential strategy for youth substance abuse prevention - science-based drug education integrated into the high school science curriculum. Through this pilot study we propose to: (1) demonstrate that this new strategy shows promise, and (2) estimate the effect size for the intervention.

Detailed description

NIDA, in recent years, has put resources into summarizing and synthesizing cutting-edge medical and basic science research discoveries about the short-term and long-term effects of drug use on the developing brain. One outcome of this results was the production of a science-based drug education program entitled The Brain: Understanding Neurobiology Through the Study of Addiction. This is a 5-lesson module for high school science classes that teaches about brain structure and function, how drugs affect and change the biology and chemistry of the brain, how addiction occurs in the brain, and that addiction is a chronic, recurring disease. However, the effect of receipt of this program on students' substance use knowledge, attitudes, perceived risk of harm, and behavior has not been systematically evaluated to date. The specific aims of this project are: 1. To evaluate the effects of receipt of the curriculum on specific cognitive contributors to substance use including a)students' knowledge about the short- and long-term effects of substance use on the brain; b)perceived risk of harm from substance use; and c)intention to use substances in the next 3 months. 2. To evaluate the effects of the intervention on actual substance use behavior. We hypothesize that the effectiveness of this approach may be modified by the students' level of prior and current substance use, with the effect being stronger among those who have not already initiated use, or among those who have very low use. Therefore, we will specifically examine whether the intervention a)prevents substance use initiation among students who had no previous use, b)stops use among students with low lifetime use, and c) reduces use among those with higher levels of use.

Interventions

OTHERdrug prevention curriculum

Participants in the experimental arm of the study will receive the 5-lesson, science-based drug prevention curriculum in their science classes.

Sponsors

Boston Public Schools
CollaboratorOTHER
Boston Children's Hospital
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
14 Years to 19 Years
Healthy volunteers
Yes

Inclusion criteria

* Student in 9th/10th/11th grade science classes at Fenway High School at start of study or student in 11th grade science classes at Boston Arts Academy at start of study * Parental permission to participate

Exclusion criteria

* No parental permission to participate * Unable to read English

Design outcomes

Primary

MeasureTime frame
Lifetime, past 6 month and past 30 day use of substancesPre-intervention, immediate post-intervention, 6-7 month post-intervention

Secondary

MeasureTime frame
Frequency and quantity of substance usePre-intervention, immediate post-intervention, 6-7 months post-intervention
Knowledge about effects of substance use on the brainPre-intervention, immediate post-intervention, 6-7 months post-intervention
Perceived risk of harm of substance usePre-intervention, immediate post-intervention, 6-7 months post-intervention
Intention to use substances in the next 3 monthsPre-intervention, immediate post-intervention, 6-7 months post-intervention

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026