Head and Neck Cancer, Head and Neck Cancers
Conditions
Brief summary
To see if a limited sampling of tumor tissue from human subjects is a feasible way to gather adequate tissue for cancer stem cell quantification.
Interventions
PROCEDUREtumor biopsy
Sponsors
Stanford University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. Patients with malignant tumors seen at the Stanford University Cancer Center. Eligible patients will have a diagnosis of squamous cell carcinoma (HNSCC) and will have been seen in the Stanford Head and Neck Oncology Program. A decision to undergo surgery at Stanford will have been made, prior to recruiting patients for the study, and prior to obtaining the samples during surgery. (Histological confirmation of the diagnosis need not be made prior to obtaining consent.) 2. A definitive resection of a malignant tumor is planned. 3. Surgeon judgment that the definitive procedure will not be compromised by including * FNA * Core needle biopsy * Cup forceps or punch biopsy of\<4mm. 4. Informed consent documented prior to procedure
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quantification of the cancer stem cell population by flow cytometry | 1 month |
Countries
United States
Outcome results
None listed