Effect of Deep Brain Stimulation on Lower Urinary Tract Function

Effect of Deep Brain Stimulation (DBS) on Lower Urinary Tract (LUT) Function

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00610233

Enrollment

Registered

2008-02-07

Start date

2005-06-30

Completion date

2014-06-30

Last updated

2014-09-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Movement Disorder, Urinary Tract Disease

Keywords

deep brain stimulation, urodynamics

Brief summary

The precise mechanisms underlying cerebral regulation of lower urinary tract (LUT) function are still poorly understood. Patients with deep brain stimulation (DBS) offer the unique opportunity to investigate the role of different cerebral centers on LUT function. We hypothesize that DBS has a significant effect on LUT function and that these effects depend on the specific stimulated cerebral center.

Interventions

PROCEDUREdeep brain stimulation ON

deep brain stimulation in the ON state

PROCEDUREDeep brain stimulation OFF

Urodynamic investigation with deep brain stimulation in the OFF state

Study design

Allocation

NON_RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients with deep brain stimulation (DBS)

Exclusion criteria

* Pregnancy * Age \<18 years

Design outcomes

Primary

Measure	Time frame
Effect of deep brain stimulation (DBS) on urodynamic parameters	immediately and 3 months after study inclusion

Secondary

Measure	Time frame
Changes in questionnaire data due to deep brain stimulation (DBS)	3 months

Countries

Switzerland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026