Atopic Dermatitis
Conditions
Keywords
atopic dermatitis, pimecrolimus, hydrocortison, Optical Coherence Tomography
Brief summary
to explore the atrophogenic potentials of hydrocortison 1% cream and pimecrolimus 1% cream on unaffected forehead skin
Interventions
twice a day one fingertip at a 2 times 2 cm2 area of uninvolved skin on the lateral forehead for 4 weeks
DRUGhydrocortison 1% cream
twice a day one fingertip at a 2 times 2 cm2 area of uninvolved skin on the lateral forehead for 4 weeks
Sponsors
Technische Universität Dresden
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
* age 18-60 years * diagnosis of atopic dermatitis (Hanifin & Rajka Criteria) * patients with atopic dermatitis not affecting the forehead
Exclusion criteria
* pregnancy / nursing mothers * women in reproductive age without adequate contraception * severe atopic dermatitis (IGA \>= 4) * UV-Therapy in past 4 weeks * patients receiving any topical treatment on the face in past 6 month
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| thickness of epidermis | 4 weeks |
Secondary
| Measure | Time frame |
|---|---|
| thickness of dermis | 4 weeks |
Countries
Germany
Outcome results
None listed