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Albumin Use in Burn Patients

Albumin Use in Burn Patients

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT00609414
Enrollment
460
Registered
2008-02-07
Start date
2005-01-31
Completion date
2008-10-31
Last updated
2011-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Burns

Keywords

Burns, Albumin, Fluid Resuscitation

Brief summary

This is a study of why and how physicians use albumin during the first 72 hours after a burn injury.

Detailed description

While albumin has been a part of burn resuscitation for many years, its use remains varied and controversial. The purpose of this study is to describe the current practices of albumin administration during the first 72 hours after a burn injury. Participating sites will collect data on patients with at least a 20% Total Body Surface Area (TBSA) burn. Information will be recorded on type and extent of burn injury, basic demographic data, co-morbidities, outcomes and, for the first 72 hours post injury, if albumin was used and why, amount of resuscitation fluids and urine output, and use of vasopressors and diuretics. Each participating site will retrospectively review 20 charts of consecutive admissions with at least a 20% TBSA burn. In addition, each site will collect data prospectively on 20 more patients with 20% TBSA burns. Prospective data is requested in order to capture as close as possible to real time the reasons physicians choose to give albumin. No Protected Health Information (PHI) will be recorded. Data will be analyzed for patterns of albumin use and reasons for albumin administration.

Interventions

None listed

Sponsors

University of North Carolina, Chapel Hill
Lead SponsorOTHER

Study design

Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* Burn Injury, with and without inhalation injury

Exclusion criteria

* \<20% Total Body Surface Area Burned * Comfort care only for the burn injury

Countries

Canada, United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026