Cystic Fibrosis
Conditions
Keywords
cystic fibrosis, exercise, perceived exertion, aerobic fitness, lung function, health related quality of life, self-regulated exercise
Brief summary
The aim of this study is to test the effect of a 6-month program of self-regulated, home-based exercise with telephone reinforcement on the cardiorespiratory fitness, pulmonary function and health-related quality of life of children with cystic fibrosis (CF), compared to controls. Exploring the exercise experiences of the children and parents is a secondary aim.
Detailed description
CF is a life-long illness that requires complex and dynamic adjustment by the patient and family. The nursing role is vital to the multidisciplinary team approach required in providing comprehensive, individualized care for these patients. Nurses facilitate the coordination of health care efforts and support the patient and family across physical and psychosocial domains. With the well-documented correlation between exercise tolerance and both survival and HRQoL, exercise represents a critical treatment focus for CF patients. Nurses contribute to standard exercise rehabilitation programs, through education, psychosocial support, and communication. In this exercise training study, the nursing role will include: a) teaching the patients and families how to use the OMNI scale, b) confirming that they understand the home-based exercise regimen, and c) ensuring that the home-care program is properly followed by placing weekly telephone calls to assess progress and barriers. Long-term nursing application will occur via dissemination of the OMNI training manual, to be developed as part of this study, for use by CF nurses in clinics worldwide.
Interventions
BEHAVIORALSelf-Regulated Exercise with Telephone Reinforcement
The self-regulated exercise with telephone reinforcement group will engage in a three-times-a-week (or more) at home exercise regimen for 6 months during which they may choose the mode of exercise. They will receive weekly telephone calls about exercise and airway clearance. After 6 months, they will be instructed to maintain their self-regulated exercise activity for the remaining 6 months of the study, but they will not receive telephone calls
BEHAVIORALStandard Treatment
The attention control group will receive standard recommendations for exercise activity, during the first 6 months, as is common in our clinic. Also during the first 6 months, they will receive weekly telephone calls about airway clearance. For the final 6 months of the study, the attention control group will cross over to self-regulated exercise without telephone reinforcement.
BEHAVIORALQualitative Approach
A qualitative naturalistic approach is nested within the primary experimental framework to explore the experiences of the children and parents, in both groups, with the exercise regimen.
Sponsors
National Institute of Nursing Research (NINR)
University of Pittsburgh
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
10 Years to 18 Years
Healthy volunteers
No
Inclusion criteria
* CF diagnosis * age 10-18 years * reliable pulmonary function tests * living at home * able to read * able to ride a stationary bike * able to walk and/or run on a treadmill.
Exclusion criteria
* Enrolled in another intervention study * in structured aerobic activity for 30 continuous minutes 3 times per week * sibling enrolled in study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cardiopulmonary Fitness: Peak VO2 | 1 year |
Secondary
| Measure | Time frame |
|---|---|
| Cardiopulmonary fitness: VO2150 and peak power output | 1 year |
| Pulmonary function: FEV1 and sustained phonation time | 1 year |
| Health-related quality of life: Quality of well-being scale and cystic fibrosis questionnaire | 1 Year |
| Exercise experiences of children and parents: Interviews | 1 Year |
Countries
United States
Outcome results
None listed