Comparison Between Low Pressure Versus High Pressure Laparoscopic Cholecystectomy

A Prospective Randomized, Controlled Study Comparing Low Pressure Versus High Pressure Pneumoperitoneum During Laparoscopic Cholecystectomy.

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00606762

Enrollment

Registered

2008-02-05

Start date

2006-10-31

Completion date

2007-12-31

Last updated

2008-02-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cholelithiasis

Keywords

laparoscopic cholecystectomy, low pressure pneumoperitoneum

Brief summary

The physiological changes and postoperative pain are directly related with the degree of intra-abdominal pressure kept during the laparoscopy. The present study aims to examine difference between low pressure pneumoperitoneum (8 mm Hg)and High pressure pneumoperitoneum (12 mm Hg)during laparoscopic cholecystectomy in terms of pain, cardio-pulmonary function, arterial blood gas changes etc.

Interventions

PROCEDURELaparoscopic cholecystectomy

Laparoscopic cholecystectomy is performed at either 8 mm Hg or 12 mm Hg intra-abdominal pressure

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

HEALTH_SERVICES_RESEARCH

Masking

TRIPLE (Subject, Caregiver, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* symptomatic gall stone disease

Exclusion criteria

* pyocele * gangrene of gall bladder * history of cholangitis * simultaneous CBD stones * gall stone pancreatitis * who does not give consent if they will be randomized to LPLC

Design outcomes

Primary

Measure	Time frame
Pain	24 hours

Secondary

Measure	Time frame
Pulmonary function	24 hours

Countries

India

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026