Ventricular Premature Complexes
Conditions
Keywords
right ventricular outflow tract arrhythmia, sex hormone level, menstrual cycle, Gonadal Hormones
Brief summary
The purpose of this study is to determine whether the occurrence of idiopathic right ventricular outflow tract(RVOT) arrhythmia is relative to sex hormone levels in different stages of female menstrual cycle
Detailed description
The predilection site of idiopathic ventricular arrhythmia is right ventricular outflow tract ,which is called idiopathic RVOT arrhythmia , a retrospective study reported the females are susceptibility to this kind of arrhythmia and another questionaire survey of triggers for RVOT-VT initiation indicated that women have RVOT-A initiation with recognized states of sex hormonal flux , but few researches were made to study the exact relation between this kind of arrhythmia and sex hormone levels, this is the aim of our study .40 females with regular menses(20 females with RVOT arrhythmia ,20 healthy volunteers) will be screened, the Participants will undergo ECG monitoring and their blood samples will be collected at various times throughout the study.
Interventions
None listed
Sponsors
Harbin Medical University
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 45 Years
Healthy volunteers
Yes
Inclusion criteria
* Must be female * Aged 20 to 45 years, with regular menstrual cycles. * With normal BMI * Without organic heart disease * Healthy volunteers and women with RVOT arrhythmia are both being recruited.
Exclusion criteria
* Pregnancy * Use of hormonal therapy including birth control pills or other drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| number and duration of right ventricular outflow tract arrhythmia | one month |
Secondary
| Measure | Time frame |
|---|---|
| sex hormone levels | one month |
Countries
China
Outcome results
None listed