Hepatocellular Carcinoma
Conditions
Keywords
Recurrence, Survival, Immunology, Laparoscopy
Brief summary
Short-term outcomes of laparoscopic liver resection is better than those of open liver resection Laparoscopic liver resection is better than open resection in immunological aspects
Detailed description
Advantages and disadvantages of the laparoscopic compared with the open approach for liver resections 1. Advantages 1) Less postoperative ascites production 2) Reduced postoperative pain 3) Feasible in selected cirrhotics who have contraindications to open surgery 4) Less intra-abdominal adhesions (easier salvage transplantation) 5) Shorter recovery time 6) Shorter length of stay 7) Reduced financial cost 2. Disadvantages 1) No manual palpation or exploration of the liver parenchyma possible (with the pure laparoscopic approach) 2) High demand in surgical skill (especially major resections)
Interventions
PROCEDURELiver resection
Laparoscopic or Open hepatectomy
Sponsors
Seoul National University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
20 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Radiologically diagnosed hepatocellular carcinoma * Child classification A or B * Aged 20 to 80 * Informed consent taken
Exclusion criteria
* Child classification C * Extrahepatic metastasis * Tumor located in central area or adjacent to middle hepatic vein * Recurred hepatocellular carcinoma * Critically ill patient * Patient with psychiatric disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recurrence rate | 2 years after operation |
Secondary
| Measure | Time frame |
|---|---|
| Survival | 2 years after operation |
Countries
South Korea
Outcome results
None listed