Ischemic Heart Disease, Post-Operative Complications
Conditions
Keywords
Off-pump, OPCAB, EuroSCORE, high-risk patients, Quality of life, Validity of EuroSCORE
Brief summary
Previous studies comparing on-pump and off-pump operating strategy did only partially demonstrate benefits of the off-pump myocardial revascularisation.In primary end-points (MI, death, renal failure, and so on) there was no significant difference, but in secondary end-points we observed benefits resulting for patients. We would like to show the benefit of the method without extracorporeal circulation in patients with higher and hight operation risk, coming from EuroSCORE classification system (6 points and more).
Interventions
PROCEDUREOPCAB - the off-pump coronary artery bypass
surgical myocardial revascularisation without use of cardio-pulmonary bypass, using stabilising devices on beating heart
Sponsors
Charles University, Czech Republic
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* stable form of ischemic heart disease * unstable angina pectoris * acute myocardial infarction * additive EuroSCORE 6 and more * informed approval of the patient
Exclusion criteria
* significant heart valve disease, requesting surgery * aortic aneurysm requesting surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| death, heart stroke, brain stroke, renal failure, early reoperation | 30 days |
| heart stroke, brain stroke, death, renal failure, early reoperation | 30 days and 365 days |
Secondary
| Measure | Time frame |
|---|---|
| length of in-hospital stay, blood losses, number of blood-transfusion, new appeared atrial fibrillation, 1-year mortality, quality of life-angina classified by CCS in 1-year follow up, length of mechanical ventilation | 30 days and 365 days |
Countries
Czechia
Outcome results
None listed