Osteoarthritis
Conditions
Keywords
osteoarthritis, knee, total knee arthroplasty, exercise
Brief summary
Total knee arthroplasty (TKA) is performed more than 7.000 times a year in Finland most often for osteoarthritis (OA). While pain is predictably reduced, function does not typically ever reach that of age-matched, uninjured subjects. Quadriceps weakness has been implicated in the development and progression of knee OA and is a significant problem after TKA. Advance to return to normal daily activities is not sufficient to restore knee function or quadriceps strength after TKA. The aim of this study is to assess the effectiveness of progressive exercise program restoring knee strength, mobility and improving the functional outcome after primary TKA.
Detailed description
Many studies have shown, that after TKA pain decreased significantly, but muscle strength of the operated knee did not recover and may stay under the preoperative level. To find out the effects of progressive exercise program the investigators will perform, 6 weeks after TKA, a randomized clinical trial of lower extremity strength training using two subgroups of people: traditional exercise group and progressive exercise group.
Interventions
OTHERKnee muscle exercises
Home exercises three times a week, control every three months
Sponsors
Jyväskylä Central Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* primary unilateral TKA for knee osteoarthritis
Exclusion criteria
* Rheumatoid arthritis * Fibromyalgia * Bilateral TKA * Heart or lung disease, which prevent training * Unstable serious disease (cancer) * Reduced cooperation (drug, alcohol abuse, mental illness)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Functional tests, pain | baseline , 6 weeks after operation (start of training), after 12 months training | Timed-Up and Go-test, Visual analogue scale (VAS) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Knee muscle strength | baseline, 6 weeks after operation (start of training), after 12 months training | isometric strength of quadriceps and hamstrings |
| Health related quality of life | baseline and 12 months | SF-36 |
| gait analysis | baseline, 6 weeks postoperatively, 12 months | — |
Countries
Finland
Outcome results
None listed