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Oral Care Protocol for Preventing Ventilator- Associated Pneumonia

The Effectiveness of an Oral Care Protocol in Preventing Ventilator- Associated Pneumonia for Intensive Care Unit Patient

Status
Completed
Phases
Early Phase 1
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00604916
Acronym
VAP
Enrollment
53
Registered
2008-01-30
Start date
2007-03-31
Completion date
2008-01-31
Last updated
2008-01-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pneumonia

Keywords

oral hygiene

Brief summary

The Nosocomial Pneumonia remains to be a major complication for patients who were incubated with ventilation. Most cases are attributed to increased bacteria flora in oropharyngeal secretion and aspiration of those organisms. Research indicates that the Gram-Negative Bacteria grows in upper air way and trachea rapidly during the initial 2-4 hospital days and the dental plague also increased dramatically at the first 5 days. About 50% cases with prolonged intubation experienced temporal swallowing disorders and majority of them recovered 7 days post weaning. Some evidence exist suggesting that oral care could reduce bacterial flora, prevent aspiration, and subsequently decrease the incidence of ventilation-associated pneumonia for this group of high risk patients. This study aims to evaluate the effectiveness of a standardized oral care protocol in improving oral hygiene and reducing the incidence of pneumonia on a sample of surgical patients at intensive care unit.

Interventions

OTHERstandardized oral care protocol - electronic toothbrush

a standardized 20-minute oral care protocol using an electronic toothbrush to clean and moisturize oral cavity twice daily.

OTHERmimic protocol

a mimic 20-minute protocol involving moisturizing and attention control was performed for the same intervals.

Sponsors

National Taiwan University
CollaboratorOTHER
Mackay Memorial Hospital
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Investigator)

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patients newly admitted to SICU who were under ventilator support for 48\ 72 hours

Exclusion criteria

* With pneumonia present

Design outcomes

Primary

MeasureTime frame
the oral hygiene status measured by the oral assessment guide and plague indexevery 3~4days

Secondary

MeasureTime frame
The incidence of VAP defined by the Clinical Pulmonary Infection Scorea 7 day oral care protocol duration

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026