Out-of-hospital Cardiac Arrest
Conditions
Brief summary
Sudden death is a major problem in industrially developed countries. Despite a decline in ischemic heart disease mortality and the progress has been made in resuscitation, treatment of sudden death victims is frequently unsuccessful. the ideal solution would be to prevent the disease process that causes the initial episode of cardiac arrest. Parental sudden death is an independent risk factor for sudden death. So, detect a gene predisposing to sudden death may help provide better identification of subjects at high risk of cardiac arrest. This research is a genetic study of sudden cardiac death, recruited 2000 subjects in out-of-hospital cardiac arrest.
Interventions
None listed
Sponsors
Institut National de la Santé Et de la Recherche Médicale, France
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* OHCA * Aged from 18 to 75 years
Exclusion criteria
* Pregnant * People not free * Inhospital subjects * Death by other disease * Violent death
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Frequency of Single Nucleotide Polymorphism (SNP) across the entire genome | Day 1 | DNA extracted from blood cells |
Countries
France
Contacts
PRINCIPAL_INVESTIGATORXavier Jouven, PhD, MD
Institut National de la Santé Et de la Recherche Médicale, France
Outcome results
None listed