Study to Determine the Phototoxity of Atralin (Tretinoin) Gel, 0.05%

Clinical Evaluation of the Phototoxic Potential of Atralin (Tretinoin) Gel, 0.05%

Status

Completed

Phases

Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00604032

Enrollment

Registered

2008-01-29

Start date

2008-01-31

Completion date

2008-02-29

Last updated

2008-03-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Keywords

Safety when exposed to sunlight

Brief summary

To assess the potential of tretnoin gel 0.05% to produce phototoxic reactions, measured as skin reactions 24 and 48 hours after UV radiation of drug on skin.

Interventions

DRUGAtralin (tretinoin) Gel, 0.05%

Assess potential of tretinoin gel, 0.05% to produce phototoxic reactions, measured 24 and 48 hours after UV radiation of drug on the skin.

Study design

Allocation

RANDOMIZED

Intervention model

SINGLE_GROUP

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Normal healthy volunteers * 18 years of age or older

Exclusion criteria

* Less than 18 years of age

Design outcomes

Primary

Measure	Time frame
UV induced skin sensitization	4 days

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026