Clinical Evaluation of the Photoallergy Potential of Atralin Gel

Clinical Evaluation of the Photoallergy Potential of Atralin Gel (Tretinoin Gel 0.05%)

Status

Completed

Phases

Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00603772

Enrollment

Registered

2008-01-29

Start date

2008-01-31

Completion date

2008-03-31

Last updated

2008-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Keywords

Tretinoin, exposure to UV light, phototoxicity, Safety when exposed to sunlight

Brief summary

To assess the potential of tretinoin gel 0.05% and its vehicle to produce photoallergic reactions, measured as skin reactions following induction and challenge.

Interventions

DRUGAtralin (tretinoin) gel, 0.05%

Assess photoallergic reactions for tretinoin 0.05% and vehicle, measured as skin reactions following induction and challenge.

Study design

Allocation

RANDOMIZED

Intervention model

SINGLE_GROUP

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Normal, healthy volunteers * 18 years of age and older

Exclusion criteria

* Less than 18 years of age

Design outcomes

Primary

Measure	Time frame
UV Induced skin irritation	4 days

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026