Acclimatization Mechanisms During Ascent to 7500m

Acclimatization Mechanisms During Ascent to 7500m. Effects of Ascent Protocol on Acute Mountain Sickness and Cardiorespiratory Physiology

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00603122

Enrollment

Registered

2008-01-28

Start date

2005-03-31

Completion date

2005-12-31

Last updated

2014-05-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Mountain Sickness

Keywords

altitude illness, hypoxia

Brief summary

The trial evaluates the role of ascent protocol on acute mountain sickness and cardio-respiratory physiology during an ascent to Muztagh Ata (7546m). Two groups of mountaineers ascend with different acclimatization time to the summit. The prevalence and severity of symptoms of acute mountain sickness are evaluated along with physiologic variables.

Interventions

BEHAVIORALascent protocol

ascent protocol for the two groups has different acclimatization time

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 70 Years

Healthy volunteers

Yes

Inclusion criteria

* Healthy, physically fit subject * Mountaineering experience

Exclusion criteria

* Any type of cardiac or respiratory disease * Regular intake of any medication * History of high altitude pulmonary oedema * Severe acute mountain sickness at altitudes below 3500m or high altitude cerebral oedema.

Design outcomes

Primary

Measure	Time frame
acute mountain sickness	during ascent

Secondary

Measure	Time frame
mountaineering success, oxygen saturation, breathing pattern	during ascent

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Apr 3, 2026