The DINE Study-Diet Intervention to Negate Diabetes Study (Improving Weight Loss Outcomes for African Americans)

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00599040

Acronym

DINE

Enrollment

113

Registered

2008-01-23

Start date

2005-09-30

Completion date

2010-12-31

Last updated

2013-03-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetes, Hypertension, Insulin Resistance

Brief summary

The purpose of this study is to determine if what you eat affets your insulin sensitivity when you lose a small amount of weight

Interventions

BEHAVIORALThe DASH diet with weight loss

A reduced calorie diet is provided to participants based on the DASH diet.

BEHAVIORALThe DASH diet without weight loss

participants are given a weight maintainenance diet based on the DASH diet

BEHAVIORALDairy diet

participants are given a high dairy, reduced calorie diet

Study design

Allocation

RANDOMIZED

Intervention model

FACTORIAL

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

19 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* African American adults (age ≥ 19) * Obese (BMI \> or equal to 30 kg/m2) * Otherwise generally healthy

Exclusion criteria

* Diagnoses of diabetes * Malignancy or other states where weight loss is contraindicated (pregnancy * Individuals with high blood pressure on medications.

Design outcomes

Primary

Measure	Time frame
Insulin Sensitivity	8 weeks

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026