Lung Cancer, Quality of Life, Thoracotomy, Video-assisted Thoracic Surgery (VATS)
Conditions
Keywords
Lung cancer, Quality of Life, VATS, thoracotomy, 05-006
Brief summary
The purpose of this study is to see if different types of surgery for lung cancer have different effects on quality of life and pain. What we learn from this study may help us find new ways to improve the quality of life of lung cancer patients who have surgery.
Interventions
BEHAVIORALquestionnaires
QOL Measures- The following measures will be administered at Pre-Op, First Post-Op Visit 4, 8, 12 months Post-Op. Brief Pain Inventory and daily analgesic log- enrollment, patients will fill out the BPI preoperatively, postoperative days 2 to 4, initial, 4-month, 8-month and 12-month postoperative visits.
Sponsors
Memorial Sloan Kettering Cancer Center
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Patients with histologically confirmed or suspected clinical stage I non small cell lung cancer (including carcinoid tumors) based on standard staging (CT, PET, ± mediastinoscopy). * Patients offered a VATS anatomic lung resection or a standard, posterolateral thoracotomy and anatomic lung resection at MSKCC. * Patients cannot have had prior therapy, including surgery for the current lesion, systemic chemotherapy or external beam radiotherapy. * KPS ≥ 70. * Synchronous primaries within one lobe.
Exclusion criteria
* Patients who have already undergone the planned operation. * Patients who cannot tolerate segmentectomy or lobectomy. * Patients with locally advanced or metastatic disease found either preoperatively or at the time of operation. * Patients who are non- English speaking * Patients with multi-focal disease * Patients with con-current cancers * Patients with benign disease. * Patients who are unwilling or unable to return to Memorial Sloan-Kettering Cancer Center for postoperative follow-up for the first year following their operation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Determine the postoperative change in QOL and level of pain in patients with clinical stage I NSCLC undergoing VATS anatomic lung resection and for patients with clinical stage I NSCLC undergoing thoracotomy and anatomic lung resection | conclusion of study |
Secondary
| Measure | Time frame |
|---|---|
| Compare early postoperative analgesic requirements between the VATS and thoracotomy groups. | conclusion of study |
Countries
United States
Outcome results
None listed