Korean Hereditary Breast Cancer Study

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00595348

Acronym

KOHBRA

Enrollment

2250

Registered

2008-01-16

Start date

2007-11-30

Completion date

2017-05-31

Last updated

2011-05-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast Cancer, Ovarian Cancer

Brief summary

1. To evaluate the prevalence of BRCA1/2 mutation of breast cancer patients with family history of breast/ovarian cancer. 2. To evaluate the prevalence of BRCA1/2 mutation of breast cancer patients without family history, but high risk of hereditary cancer. 3. To evaluate the prevalence of BRCA1/2 mutation of family member of BRCA1/2 mutation. 4. To evaluate the prevalence of ovarian cancer of population of above 3 groups.

Detailed description

1. To find founder mutation in Korean 2. To correlation prevalence with risk evaluation 3. To find risk factors concerning life style

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

20 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Over 19 years old * Agree to this study * Breast cancer patient with family history of breast/ovarian cancer (1 subgroup) * Breast cancer patient; young age (\<40), bilateral, male, combined ovarian (2 subgroup) * Family members with 1, 2 subgroups (3 subgroup)

Exclusion criteria

* Under 20 years old * Unable to decide for oneself

Design outcomes

Primary

Measure	Time frame
Find out the prevalence of BRCA1/2 mutation of high risk breast cancer patients	6 years

Countries

South Korea

Contacts

Primary ContactKu Sang Kim, M.D, AME.

ideakims@gmail.com82-31-219-5200

Outcome results