Effects of Medical and Surgical Weight Loss on Metabolism

The Role of Adipocyte-derived Inflammatory Cytokines in the Pathogenesis of Diabetes, Dyslipidaemia, Atherosclerosis and Gastro-oesophageal Reflux Disease: the Effects of Medical and Surgical Weight Loss

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00592735

Acronym

BOS

Enrollment

Registered

2008-01-14

Start date

2007-05-31

Completion date

2012-05-31

Last updated

2016-06-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 Diabetes, Obesity

Brief summary

This study will follow ,morbidly obese subjects as they undertake weight loss before and after laparoscopic gastric banding, examining markers of glucose and lipid metabolism, adipokines and measures of body fat.

Interventions

PROCEDURElaparoscopic gastric banding

standard surgical procedure

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 70 Years

Healthy volunteers

Inclusion criteria

* morbidly obese subjects with type 2 diabetes or metabolic syndrome * age \<70

Exclusion criteria

* contra-indications to bariatric surgery

Design outcomes

Primary

Measure	Time frame
weight loss	6 months

Countries

Australia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026