Barrett's Esophagus, GERD
Conditions
Keywords
Barrett's Esophagus, Upper Endoscopy, Esophageal biopsies, Accuracy, Interobserver Agreement
Brief summary
Barrett's esophagus (BE) is a condition that often occurs in patients who have had GERD for a long time. The researchers are interested in BE because it can sometimes become a cancer in the esophagus. The way that we currently diagnose BE is by performing an upper endoscopy and looking for a change in the color of the esophagus. This color change may represent BE. If the doctor sees this, he/she may take biopsies of this area. Studies have shown that making the diagnosis of BE can be hard to make. One of the reasons why this may be is because doctors may interpret what they see differently during the procedure. In other words, they may see an esophagus that appears normal in color or abnormal in color. The purpose of this study is to compare two doctors' impressions of the appearance of the esophagus during a single endoscopy procedure.
Interventions
None listed
Sponsors
Oregon Health and Science University
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* History of (h/o) GERD * Upper GI symptoms such as acid taste in mouth, dysphagia, dyspepsia * Screening or surveillance exam for BE
Exclusion criteria
* Unable to consent * History of esophageal varices
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome will be the interobserver variability in the presence of columnar epithelium as well as the measured lengths. | one endoscopy visit |
Secondary
| Measure | Time frame |
|---|---|
| frequency of pathology-confirmed BE | one endoscopy visit |
| variables that predict endoscopic interobserver agreement and path-confirmation | one endoscopy visit |
Countries
United States
Outcome results
None listed