Atrial Fibrillation
Conditions
Keywords
hsCRP
Brief summary
The laboratory test, C-Reactive Protein (CRP), has become well established as a marker of inflammation. Recently a high CRP level (indicating an increase in inflammation) was identified as a risk factor for atrial fibrillation. We are conducting this study with patients such as yourself with atrial fibrillation who are planning to undergo cardioversion to determine what sort of relationship exists between CRP levels and atrial fibrillation. We will then look at success rates of converting atrial fibrillation to normal sinus rhythm, compared to patients' CRP levels.
Interventions
PROCEDURECardioversion
Baseline hsCRP will be drawn the morning of, prior to, cardioversion. An EKG to document the patient's rhythm will be obtained at the one-month mark
Sponsors
Creighton University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
19 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Atrial fibrillation patients referred for DC cardioversion * On stable medical therapy
Exclusion criteria
* Known chronic inflammatory states such as infections, rheumatoid arthritis or known vasculitides. * Patients having undergone recent surgery or who are on steroid therapy for any reason will be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| We hypothesize that a higher hsCRP is associated with higher failure rates in patients undergoing cardioversion for atrial fibrillation | 1 month |
Secondary
| Measure | Time frame |
|---|---|
| secondary endpoint will be if a new inflammatory disease state is diagnosed at the one-month mark. | 1 month |
Countries
United States
Outcome results
None listed