Microbial Community Composition and Dynamics in Lungs of Cystic Fibrosis Sibling Pairs

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00590330

Enrollment

Registered

2008-01-10

Start date

2007-10-31

Completion date

2009-03-31

Last updated

2011-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cystic Fibrosis

Brief summary

The purpose of this study is to identify all the bacterial species present in the respiratory tracts of patients with Cystic Fibrosis (CF), and to connect them with clinical information. Traditional culture methods of throat swab and sputum samples can only identify the most prevalent bacteria in samples, those of which there are over about 5 million bacteria per teaspoon. A recently developed method has been found to be more sensitive and can detect up to several hundred bacterial species in throat swab or sputum sample of individual CF patients.

Detailed description

This study does not include testing of any investigational drugs and this is a noninvasive study requiring only a sputum/swab sample paired with information contained in the routine clinic letters and laboratory results your CF physicians obtain at your regular clinic visits.

Interventions

None listed

Study design

Observational model

FAMILY_BASED

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

1 Years to 16 Years

Healthy volunteers

Inclusion criteria

* Between the ages of 1-16 upon enrollment * Diagnosis of Cystic Fibrosis

Exclusion criteria

* None

Design outcomes

Primary

Measure	Time frame
To identify all the bacterial species present in the respiratory tracts of patients with Cystic Fibrosis (CF).	2 years

Countries

United States

Outcome results