C-reactive Protein and Endothelial Dysfunction in Women With Glucose Intolerance

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00589355

Enrollment

Registered

2008-01-09

Start date

2002-01-31

Completion date

2008-10-01

Last updated

2020-04-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glucose Intolerance

Keywords

c-reactive protein, endothelial dysfunction, glucose intolerance

Brief summary

The goal of this study is to determine whether markers of vascular inflammation (such as c-reactive protein) can predict endothelial dysfunction (as measured by flow-mediated dilation) in postmenopausal women with glucose intolerance compared to normal controls.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

FEMALE

Age

40 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

* healthy postmenopausal women * ages 40-65

Exclusion criteria

* smokers * diabetes requiring medication

Design outcomes

Primary

Measure	Time frame
c-reactive protein	performed after screening evaluation

Secondary

Measure	Time frame
flow-mediated dilation of brachial artery	performed twice after screening visit
sex steroids	performed after screening visit

Countries

United States

Outcome results