Low Dose Ketamine as an Adjunct to Fentanyl in Outpatient Tonsillectomy

A Prospective Study of Low Dose Ketamine as an Adjunct to Fentanyl in Pediatric Patients Following Outpatient Tonsillectomy and Adenoidectomy

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00587665

Enrollment

122

Registered

2008-01-07

Start date

2006-08-31

Completion date

2007-12-31

Last updated

2017-06-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain

Keywords

Pain

Brief summary

Comparing patients receiving subanesthetic doses of Ketamine vs placebo to see if it can reduce narcotic needs for patients receiving a tonsillectomy and adenoidectomy

Interventions

DRUGketamine

Single IV dose of 0.1 mg/kg of ketamine

DRUGPlacebo

Saline given of equal volume to drug

Study design

Allocation

RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

3 Years to 12 Years

Healthy volunteers

Inclusion criteria

between 3 and 12 years of age * ASA 1 or 2

Exclusion criteria

* did not consent

Design outcomes

Primary

Measure	Time frame
amount of post op narcotic use	5 days

Secondary

Measure	Time frame
degree of nausea and vomiting	5 days

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026