Neurobehavioral Manifestations, Neurologic Manifestations
Conditions
Keywords
cognition, cognition disorders, executive function, cognitive control, attentional control, biomedical enhancement, cognitive enhancement, computerized, computer-based, video game
Brief summary
Control processes are classes of brain activity that initiate, coordinate, synchronize, and regulate elemental cognitive functions for the conduct of goal-directed behavior. The proposed research investigates whether exposure to a computer-based training protocol designed to enhance cognitive control processes will improve cognitive performance in healthy older adults.
Detailed description
The proposed research investigates whether exposure to a computer-based training protocol designed to enhance cognitive control processes will improve cognitive performance in healthy older adults. Cognitively normal adults aged 60-75 will be randomized into three experimental groups: 1) Video game play with training strategy; 2) Video game play without training strategy (Active Control); 3) Minimal contact (Passive Control). Subjects in Groups 1 and 2 will be instructed to play the complex, high-demand video game, Space Fortress, for 36 one-hour sessions over 12 weeks. Subjects in Group 3 will receive all assessments but will not play the computer game.
Interventions
36 one-hour sessions over 12 weeks
Sponsors
Study design
Eligibility
Inclusion criteria
* Age 60-75 * Willingness to adhere to training protocol * Adequate English proficiency
Exclusion criteria
* Known history of cognitive impairment, dementia, stroke, seizure disorder, or other neuropsychiatric condition judged to impact cognitive performance * Taking medications known to influence cognitive performance * Sensory (e.g. visual, auditory) or physical (e.g. severe arthritic, orthopedic, neurologic) impairment incompatible with use of a standard computer workstation. * Enrolled in a concurrent study that could affect the outcome of this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognitive-experimental tasks | Week 1, 6, 12, 24 |
| Neuropsychological testing | Week 1, 12, 24 |
Countries
United States