Parkinson's Disease
Conditions
Brief summary
The purpose of this study is to determine the effect of deep brain stimulation surgery on movement-related cortical potentials in patients with Parkinson's disease.
Detailed description
Patients who have had deep brain stimulation surgery for Parkinson's disease at Mayo Clinic Arizona will have electroencephalographic (EEG) measurements with the stimulator on followed by EEG measurements with the stimulator off. Patients who are scheduled to have deep brain stimulation surgery for Parkinson's disease will have EEG measurements before and after surgery.
Interventions
PROCEDUREDeep brain stimulation surgery.
Deep brain stimulation surgery.
Sponsors
Mayo Clinic
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
40 Years to 82 Years
Healthy volunteers
No
Inclusion criteria
* Patients who have had deep brain stimulation surgery for Parkinson's disease at Mayo Clinic Arizona, or who are scheduled to have deep brain stimulation surgery for Parkinson's disease at Mayo Clinic Arizona.
Exclusion criteria
* Patients unable to do repetitive dorsiflexion of the wrist due to orthopedic problems. * Pregnant women. * Prisoners or institutionalized individuals.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary measures are six EEG bereitschaftspotential areas and amplitudes. | 12 months |
Secondary
| Measure | Time frame |
|---|---|
| Unified Parkinson's disease rating scale score. | At time of EEG measurement. |
Countries
United States
Outcome results
None listed