Cytokine Kinetics Test to Assess the Presence or Absence of Tolerance in Organ Transplant

Cytokine Kinetics Assay to Assess the Presence or Absence of Tolerance in Organ Transplant Recipients

Status

Terminated

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00585858

Enrollment

Registered

2008-01-03

Start date

2006-09-30

Completion date

2008-06-30

Last updated

2016-05-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Kidney Transplantation, Liver Transplantation

Brief summary

The purpose of this pilot study is to determine if there is clinical correlation between the CKT and transplant recipients who are known to be on minimal or no immunosuppression (presumed tolerant) and those who are on conventional amounts of immunosuppression and have either experienced rejection (presumed hyper-responsive to donor) or have not experienced rejection (unknown responsive state).

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Yes

Inclusion criteria

* Kidney or liver transplant recipients for whom donor cells are available

Exclusion criteria

* HcT \<32%

Design outcomes

Primary

Measure	Time frame
Correlation between cytokine kinetics test and clinical status of subject	1 year

Countries

United States

Outcome results