Keratoconus
Conditions
Brief summary
The objective of this study is to determine if corneal topography can be used to predict the fluorescein pattern of keratoconus lenses on the eye. A corneal topography image will be taken and the computer selected lens will be placed on the eye. After placement of the lens color photographs will be taken of the eye's fluorescein pattern and compared to the computer predicted pattern.
Detailed description
Subject population: keratoconus patients who have not undergone corneal surgery 100 subjects who come to UIHC for their contact lens care. We will approach them at their visit. We will not call potential participants from a database. If topography is impossible to capture. Concommitant Corneal Disease Minors will be excluded
Interventions
None listed
Sponsors
Christine Sindt
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
18 yrs of age or older with diagnosis of keratoconus and contact lens wearer
Exclusion criteria
Noncommittant corneal disease or surgery Inability to capture topography measurement
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Number of Participants With an Observable Difference Between Virtual Versus Actual Fluorescein Patterns | Baseline first visit | Comparison of fluorescein patterns of rgp contact lens. Bearing and elevation fluorescein patterns will be compared between the actual (photo) and theoretical (computer generated) fluorescein patterns using standard clinical means. |
Countries
United States
Participant flow
Participants by arm
| Arm | Count |
|---|---|
| Corneal Topographer Flourscein Patterns Use corneal topography to evaluate fluorescein patter of rgp contact lens
Comparison of fluorescein patterns: Compare trial contact lens fitting to fitting contact lenses based on corneal topography measurement | 18 |
| Total | 18 |
Baseline characteristics
| Characteristic | Corneal Topographer Flourscein Patterns |
|---|---|
| Age, Categorical <=18 years | 0 Participants |
| Age, Categorical >=65 years | 0 Participants |
| Age, Categorical Between 18 and 65 years | 18 Participants |
| Region of Enrollment United States | 18 Participants |
| Sex: Female, Male Female | 8 Participants |
| Sex: Female, Male Male | 10 Participants |
Adverse events
| Event type | EG000 affected / at risk |
|---|---|
| deaths Total, all-cause mortality | 0 / 18 |
| other Total, other adverse events | 0 / 18 |
| serious Total, serious adverse events | 0 / 18 |
Outcome results
Primary
Number of Participants With an Observable Difference Between Virtual Versus Actual Fluorescein Patterns
Comparison of fluorescein patterns of rgp contact lens. Bearing and elevation fluorescein patterns will be compared between the actual (photo) and theoretical (computer generated) fluorescein patterns using standard clinical means.
Time frame: Baseline first visit
| Arm | Measure | Value (NUMBER) |
|---|---|---|
| Corneal Topographer Flourscein Patterns | Number of Participants With an Observable Difference Between Virtual Versus Actual Fluorescein Patterns | 0 participants |