Effect of Coffee on Gastro-Esophageal Disease in Patients With Symptoms of Reflux

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00584259

Enrollment

Registered

2008-01-02

Start date

2006-05-31

Completion date

2010-01-31

Last updated

2010-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

GERD

Keywords

GERD, Gastro-Esophageal Disease

Brief summary

Investigation evaluating the effect of coffee on gastro-esophageal reflux disease.

Detailed description

Many patients with gastro-esophageal reflux disease (GERD) report that drinking coffee causes heartburn. The purpose of this study is to investigate the effects of coffee on gastro-esophageal acid reflux, and its relation to esophageal motility parameters in patients who are already scheduled to undergo 48 hour wireless pH testing as a result of having symptoms suggestive of GERD. The specific aims are to evaluate the effects of coffee on GERD during daily life and to elucidate the underlying pathogenic mechanism by which coffee induces reflux.

Interventions

OTHERCoffee

3 cups of coffee over a 24 hour period

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

SUPPORTIVE_CARE

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* persons undergoing wireless pH testing for diagnosis and treatment of GERD

Exclusion criteria

* those under the age of 18 * pregnant and lactating women * those who do not meet the inclusion criteria

Design outcomes

Primary

Measure	Time frame
coffee leads to reflux events	48 hours

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026