Atrial Fibrillation, Congestive Heart Failure
Conditions
Keywords
Atrial Fibrillation, ICD, BiV ICD, CHF, Congestive Heart Failure, AF
Brief summary
Single center investigator initiated sponsored by Guidant Boston Scientific Corp. to evaluate the benefit of ventricular rate regularization (VRR) in patients with congestive heart failure (CHF) and significant atrial fibrillation (AF) burden.
Interventions
None listed
Sponsors
Guidant Corporation
University of California, Davis
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
* Be between 18-85 years old * Be willing and able to give informed consent * Patient currently has a CRT-D or ICD with \> 20% atrial fibrillation burden as recorded by defibrillator follow up report or a history of atrial fibrillation prior to implant. * Patient has the ability to complete a Six minute walk test with the only limiting factors to be fatigue or shortness of breath.
Exclusion criteria
* Expected mortality less than 6 months due to non-cardiac causes. * Pregnant women. * Creatinine greater than or equal to 2.5 mg/dl. * Anemia (HCT less than 30) * COPD causing significant dyspnea * Orthopedic problems affecting 6 minute walk.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improved quality of life, reduced emergency room visits and hospitalization for congestive heart failure symptoms. | 6 months |
Outcome results
None listed