Water and the Gastropressor Response - Diurnal Variability

Water and the Gastropressor Response - Diurnal Variability (Specific Aim 1.3)

Status

Active, not recruiting

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00581373

Enrollment

Registered

2007-12-27

Start date

2007-08-31

Completion date

2029-12-31

Last updated

2025-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Orthostatic Hypotension

Keywords

water, orthostatic hypotension, blood pressure

Brief summary

We will test the null hypothesis that there is no diurnal (morning to afternoon)variability in the blood pressure response to the ingestion of water 16 oz.

Detailed description

We will test the null hypothesis that there is no diurnal (morning to afternoon)variability in the blood pressure response to the ingestion of water 16 oz. This will involve having participants ingest 16 oz water rapidly in the morning and in the afternoon.

Interventions

OTHERwater 16 fl oz

water 16 fl oz in AM and repeat in late afternoon

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* orthostatic intolerance

Exclusion criteria

* pregnancy

Design outcomes

Primary

Measure	Time frame	Description
blood pressure	1 day	peak systolic blood pressure within 60 min of ingestion

Secondary

Measure	Time frame	Description
heart rate	1 day	heart rate at peak BP within 60 min of ingestion

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026