Disorder of Pleura and Pleural Cavity
Conditions
Brief summary
The researcher can use Optical coherence tomography a near-infrared diode to emit light that can produce images of the specimen under investigation and provide information about tissue abnormalities without causing damage.
Detailed description
The researcher can use Optical coherence tomography endoscopic imaging to improve diagnosis and treatment of airway and pleural malignancy. In the events of burn injury and smoke inhalation injury, the Optical coherence tomography can determine the change of the airway tissues and severity of airway injury. During endoscopic procedure the lesions will be biopsied and prepared by standard histologic methods. The Optical coherence tomography endoscopic imaging can measured histologic of the tissue samples and compared to standard histologic examination. The Optical coherence tomography endoscopic imaging can measured the epithelial thickness and compared to visual inspection of the mucosa on bronchoscopy.
Interventions
Optical Coherence Tomography imaging
Sponsors
Beckman Laser Institute University of California Irvine
University of California, Irvine
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adult 18 or older, male or female. * Plans for bronchoscopic with possible biopsy procedures.
Exclusion criteria
* Age less than 18 years of age * Not plan for bronchoscopic with possible biopsy procedures. * Pregnant or breastfeeding.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| histopathology | up to 4 weeks |
Countries
United States
Outcome results
None listed