PreTerm Birth, PreTerm Neonate
Conditions
Keywords
PreTerm Birth, PreTerm Neonate, High risk pregnancy, Preterm Baby, Premature Baby, Cord Clamping, Milking the cord
Brief summary
To determine the short and long term effects of placental transfusion at birth by milking and delayed cord clamping of the umbilical cord in neonates born between 24 weeks 0 days and 34 weeks 0 days weeks' gestation.
Detailed description
This study is intended to be a randomized controlled trial comparing immediate cord clamping which represents the current standard of care at Oklahoma University Medical Center with delayed cord clamping among preterm neonates born between 24 weeks and 34 weeks 0 days weeks' gestation. Allocation sequence will be generated by simple randomization using random number table in the stratum 24-28 weeks 6 days and 29 weeks to 34 weeks 0 days weeks' gestation stratum.
Interventions
PROCEDUREDelayed Cord Clamping
Delayed Cord Clamping: 30-35 seconds after birth
PROCEDUREImmediate Cord Clamping
Immediate Cord Clamping: within 5 seconds of birth
Sponsors
University of Oklahoma
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 50 Years
Healthy volunteers
Yes
Inclusion criteria
* Singleton pregnancies * Signed consent to participate in the trial
Exclusion criteria
* Major fetal anomaly or known fetal chromosomal abnormalities * Multiple gestation * Mothers with pregestational and gestational diabetes * Refusal to participate in the trial
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To determine the short and long term effects of placental transfusion at birth by milking and delayed cord clamping of the umbilical cord in neonates born between 24 weeks 0 days and 34 weeks 0 days weeks' gestation. | 2 years |
Countries
United States
Outcome results
None listed