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Action of Caffeinated and Decaffeinated Espresso on Autonomic Function

Short-term Autonomic Effects of Caffeinated and Decaffeinated Espresso in Young Healthy Individuals

Status
Terminated
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00576030
Enrollment
77
Registered
2007-12-18
Start date
2007-01-31
Completion date
2008-10-31
Last updated
2010-07-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Influence of Espresso on Heart Rate Variability

Brief summary

More than 80% of the population in the USA consume coffee each day. However there not many studies on change of heart rate variability and placebo effects after consumption of coffee. In our study we aim to test the following hypotheses: 1. Habitual caffeinated espresso coffee drinkers show an increase in blood pressure, heart rate variability and parasympathetic activity (high frequency band) of the heart. 2. Non-habitual caffeinated espresso coffee drinkers show an increase of blood pressure. The heart rate variability and the parasympathetic activity of the heart will decrease. 3. Caffeinated or decaffeinated espresso induces comparable changes in habitual or non-habitual coffee drinkers.

Interventions

OTHERhab cof with water

habitual coffee drinker provided with water

OTHERhab cof with dec espresso

habitual coffee drinkers given decaffeinated espresso

OTHERhab cof with caf espresso

habitual coffee drinkers given caffeinated espresso

OTHERnon-hab cof with water

non-habitual coffee drinkers given water

OTHERnon-hab cof with dec espresso

non-habitual coffee drinkers given decaffeinated espresso

OTHERnon-hab cof with caf espresso

non-habitual coffee drinkers given caffeinated espresso

Sponsors

Charite University, Berlin, Germany
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
TRIPLE (Subject, Caregiver, Investigator)

Eligibility

Sex/Gender
ALL
Age
18 Years to 50 Years
Healthy volunteers
Yes

Inclusion criteria

* 18- 50 years old, healthy

Exclusion criteria

* Medication, obese(BMI \> 30)

Design outcomes

Primary

MeasureTime frame
Heart rate variability70 minutes

Secondary

MeasureTime frame
blood pressure70 min.

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026