Effect of Conjugated Linoleic Acid on Body Fat in Overweight Children

Effect of CLA Supplementation on Body Fat Accretion Among Children Who Are Overweight or at Risk of Overweight

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00575991

Enrollment

Registered

2007-12-18

Start date

2007-01-31

Completion date

2008-09-30

Last updated

2012-03-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Overweight

Keywords

conjugated linoleic acid, body fat, children, overweight

Brief summary

The prevalence of overweight children has increased dramatically over the last decade, and many overweight children will remain overweight as adults. Conjugated linoleic acid (CLA), a naturally occurring dietary fatty acid, has shown promising results in reducing body fat among adults, and we propose to test the efficacy of CLA supplementation on body fat accretion in 6 to 10 year old children who are overweight or at risk of overweight.

Interventions

DIETARY_SUPPLEMENTConjugated linoleic acid

3 grams per day of 80% CLA in safflower oil (2.4 grams active CLA isomers in triglyceride form)

Study design

Allocation

RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

ALL

Age

6 Years to 10 Years

Healthy volunteers

Yes

Inclusion criteria

* age 6 to 10 years * body mass index greater than 85th percentile * Tanner stage I

Exclusion criteria

* medical condition * dairy allergy

Design outcomes

Primary

Measure	Time frame
body composition using DXA	6 months

Secondary

Measure	Time frame
blood chemistry variables including fasting glucose and insulin, lipids, and liver enzymes	6 months

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026