Spasticity
Conditions
Keywords
spasticity, rhizotomy, surgery
Brief summary
The purpose of this study is to determine the safe and effective levels of optical stimulation in peripheral nerves of humans otherwise undergoing nerve lesioning in surgery.
Detailed description
The purpose of this study is to determine the safe and effective levels of optical stimulation in peripheral nerves of humans otherwise undergoing nerve lesioning in surgery, namely children undergoing selective rhizotomy for treatment of medically refractory spasticity.
Interventions
PROCEDURERhizotomy for children with spasticity
Optical Stimulation versus electrical stimulation in children who need Rhizotomy Surgery for spasticity
Sponsors
Vanderbilt University
Study design
Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
3 Years to 17 Years
Healthy volunteers
No
Inclusion criteria
* Children over the age of 3 and younger than 17 years * Children who have failed appropriate medical therapy and are recommended for selective rhizotomy to treat spasticity by the pediatric neurosurgeon * Children who would normally undergo electrodiagnostic testing including EMG monitoring for physiologic testing during surgery * Surgery must be performed at the Vanderbilt University Children's Hospital
Exclusion criteria
* Patients in which a segment of the nerve (up to 2cm) cannot likely be identified at the time of surgery as determined by the pediatric neurosurgeon * Children not undergoing routine selective rhizotomy for medically refractory spasticity as determined by the pediatric neurosurgeon * Children who are medically unstable to tolerate an additional 20 minutes of experimental testing during the surgery * Women who are pregnant will be excluded from this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| A brief series of optical versus electrical stimulation of the nerve will be used to measure the efficacy of optical stimulation | 4 hours |
Countries
United States
Outcome results
None listed