Perennial Allergy to House Dust Mite and/or Cat
Conditions
Brief summary
The purpose of the study is to test the efficacy of a vaccine against house dust mite and/or cat allergy compared to placebo in adult patients.
Interventions
DRUGCYT003-QbG10
6 subcutaneous injections
Sponsors
Cytos Biotechnology AG
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Mild to moderate perennial allergic rhinoconjunctivitis due to hypersensitization towards house dust mite and/or cat allergens
Exclusion criteria
* Clinical relevant other allergies (perennial or seasonal) that could potentially interfere with the patient's study treatment schedule or assessments. * Use of any concomitant medication that could affect the patient's study treatment response or assessment results. * Any clinically relevant concomitant disease as judged by the investigator. * Pregnancy or female planning to become pregnant during the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Conjunctival provocation test with allergen and rhinoconjunctivitis symptoms in daily life | on 4 occations over 1 year |
Secondary
| Measure | Time frame |
|---|---|
| Safety and tolerability of the vaccine by collection of adverse events | at each visit |
Countries
Estonia, Latvia, Lithuania
Outcome results
None listed