A Randomised Study Comparing Tissue Conservation in Conventional Versus Mohs' Surgery of Basal Cell Carcinoma

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00571363

Enrollment

Registered

2007-12-12

Start date

2004-01-31

Completion date

2006-12-31

Last updated

2007-12-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Carcinoma, Basal Cell

Brief summary

We have compared to types of surgery to assess which one leaves the smaller surgical defect.

Detailed description

Patients with a clinical diagnosis of a nodular basal cell carcinoma of less than 1 centimetre and 1 centimetre away from eyes, nose and ears were either randomized to undergo Mohs Micrographic Surgery or standard surgical excision. After the tumour had been removed the defect was measured.

Interventions

PROCEDUREstandard surgery

excision with 4 mm margins

PROCEDUREMohs micrographic surgery

excision of basal cell carcinoma with 2 mm margins and immediate examination of margins for residual tumour. residual tumour was excised until complete tumour removal was achieved.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

BASIC_SCIENCE

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Subjects with a clinical diagnosis of a nodular basal cell carcinoma of less than 1 cm, 1 cm away from eye, nose or ears

Exclusion criteria

* Subjects of less than 18 years of age * Subjects unable to comply with instructions, * Immunosuppressed subjects

Design outcomes

Primary

Measure	Time frame
defect size after surgery	immediately after surgery

Countries

United Kingdom

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Apr 2, 2026