Lacrimal Duct Obstruction
Conditions
Keywords
Primary,silicone tube,revision,mitomycin C,endoscopic DCR
Brief summary
Endoscopic dacryocystorhinostomy (EN-DCR) is an effective procedure when treating saccal and postsaccal obstructions of the nasolacrimal pathway. The benefit of silicone tubing after DCR is still controversial. We conducted a prospective, randomized study in order to evaluate 1) the necessity of bicanalicular silicone tubes after primary EN-DCR, 2) efficacy of the perioperative Mitomycin C for the prevention of adheesion and re-stenosis of rhinostomy site in revision EN-DCR, 3) the subjective symptoms and QoL changes before and after DCR-operation.
Interventions
PROCEDUREDCR with no tubes or mitomycin
The patients were randomized into the two study groups, either with or without the insertion of a bicanalicular silicone tube after primary DCR. In revision group patients were randomized into the two groups,ether with or without application of mitomycin C after DCR
Sponsors
Kuopio University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Intervention model description
DCR with/ without tubes Revision DCR with/ without mitomycin
Eligibility
Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
* Adults (age \> 18), ASAI-III, and were scheduled for primary or revision lacrimal pathway surgery due to recurrent or chronic watering eyes or conjunctival discharge. * Patients were excluded if they had previous nasolacrimal surgery, malignancy in the paranasal sinuses, nasal cavity, or lacrimal pathway, presaccal obstruction, pregnancy or lactation, or mental disability.
Exclusion criteria
* Malignancy in the paranasal sinuses, nasal cavity, or lacrimal pathway, presaccal obstruction, pregnancy or lactation, or mental disability.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The success rate after primary DCR with and without silicone tubes. The success rate after revisio DCR with and without Mitomycin C. | 5 years |
Secondary
| Measure | Time frame |
|---|---|
| The EN-DCR operation influence on the patients subjective symptoms and QoL before and after operation. | 5 years |
Countries
Finland
Outcome results
None listed