Supplementation With Vitamin D, Calcium or Both on Calcium Absorption and Bone Mineral Content in Children With JRA

Effect of Supplementation With 2000 International Units (IU) Vitamin D, 1gm Calcium or Both on Calcium Absorption and Bone Mineralization in Children With Juvenile Rheumatoid Arthritis

Status

Completed

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00570934

Enrollment

Registered

2007-12-11

Start date

1995-03-31

Completion date

2002-02-28

Last updated

2016-10-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Juvenile Rheumatoid Arthritis

Brief summary

2000 international units (IU) vitamin D, 1 gram (gm) calcium, or both given to children with Juvenile Rheumatoid Arthritis (JRA) may increase percent true calcium absorption, bone mineral turnover and/or bone mineralization.

Detailed description

Supplementation With 2000 IU Vitamin D, 1 gm Calcium or Both on Calcium Absorption and Bone Mineralization in Children With Juvenile Rheumatoid Arthritis may increase percent true calcium absorption, bone mineral turnover and/or bone mineralization.

Interventions

DIETARY_SUPPLEMENTCholecalciferol

2000IU Cholecalciferol P.O. Q.D.

DIETARY_SUPPLEMENTCalcium

1 gm calcium as calcium carbonate

DIETARY_SUPPLEMENTCalcium and cholecalciferol

2000IU cholecalciferol and 1 gm calcium P.O. Q.D. for 6 months

DRUGPlacebo

Placebo

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

TREATMENT

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

3 Years to 15 Years

Healthy volunteers

Inclusion criteria

* Juvenile Rheumatoid arthritis

Exclusion criteria

* Steroid use

Design outcomes

Primary

Measure	Time frame
Percent true calcium absorption	After 6 months of treatment

Secondary

Measure	Time frame
Bone Mineralization by Dual Energy x-ray absorption	After 6 months treatment plus 3 month washout

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026