Muscular Strengthening for Paretic Knee Flexor and Extensor by Conventional Physiotherapy on Chronic Hemiplegic Stroke Patients

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00570570

Acronym

RenforcHémi

Enrollment

Registered

2007-12-11

Start date

2008-05-31

Completion date

2013-12-31

Last updated

2015-08-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemiplegia, Stroke

Keywords

stroke, hemiplegia, gait, Strengthening, Physiotherapy

Brief summary

Gait impairment remain one of the main problem for hemiplegic stroke patients. After the 6 first months, stroke patients are classically described with moderate or no improvement. Here, we want to compare the effectiveness of a flexor and extensor paretic knee muscular strengthening program with conventional physiotherapy delivered by the local physiotherapist of the patient, in a very ecological way.

Detailed description

Gait impairment remain one of the main problem for most of chronic hemiplegic stroke patients. After the 6 first months, stroke patients are classically described with moderate or no improvement for motor skills. However, physiothertapy is very often delivered to try to increase motor performance. Here, we want to compare the effectiveness of a flexor and extensor paretic knee muscular strengthening program with conventional physiotherapy delivered by the local physiotherapist of the patient, in a very ecological way. Patients will be randomly affected to one group with the same amount of physiotherapy (at least 3 times weekly for 6 weeks). Assessment will be done blindly by another physiotherapist, before, after the 6-week treatment and 6 weeks later to evaluate immediate and remaining benefits of each treatment.

Interventions

PROCEDUREMuscular Strengthening for paretic knee flexor and extensor

thrice a week during 6 weeks

OTHERconventional physiotherapy

trice a week during 6 weeks

Study design

Allocation

RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Hemipegia due to ischaemic or hemorrhagic stroke more than 6 months ago * 1st and unique cerebral lesion (Xscan or MRI) * ability to walk 15 m with or without cane or crutch * able to understand and give approved consent * quadriceps at 3/5 (MRC) or stronger

Exclusion criteria

* Current treatment with botulinum toxin for spasticity of the paretic flexor or extensor of the knee * Cardiovascular disease contra-indicating effort and strengthening * Pregnancy * Evolving pathology * Rheumatic disease of the knee contraindicating strengthening * Aphasia with severe comprehension impairment

Design outcomes

Primary

Measure	Time frame
Gait comfortable speed	3 months

Secondary

Measure	Time frame
gait analysis (gait maximal speed, kymographic and dynamometric analysis, quality of gait parameter) FIM MOS-SF36 Spasticity (Tardieu Scale)	3 months

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026