Left Atrial Volume and Function Evaluation in Patients With Obstructive Sleep Apnea

Left Atrial Volume and Function in Patients With Obstructive Sleep Apnea Assessed by Real Time Three Dimensional Echocardiography

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00570115

Enrollment

106

Registered

2007-12-10

Start date

2007-06-30

Completion date

2007-11-30

Last updated

2012-05-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sleep Apnea Syndromes

Keywords

Sleep Apnea Syndromes diastolic disfunction left atrium

Brief summary

The purpose of this study is to determine whether patients with obstructive sleep apnea have any changes in left atrial morphology and function evaluated by echocardiography three dimensional

Detailed description

Several studies have been suggesting that Obstructive Sleep Apnea contributes to deterioration of left ventricular diastolic function . It may lead to atrial myocardium stretching and enlargement which may be associated to increased risk of cardiovascular events. We hypothesized that morphological and functional LA changes might be found using three dimensional echo, and that such alterations are related to obstructive sleep apnea presence.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

30 Years to 70 Years

Healthy volunteers

Yes

Inclusion criteria

* Age from 30 to 70 * Apnea-hypopnea index \> 5 by polysomnography

Exclusion criteria

* Any cardiac disease * Poor imaging quality by mean of echocardiography * non-sinusal Rhythm

Design outcomes

Primary

Measure	Time frame
Left Atrial enlargement	1 day

Countries

Brazil

Outcome results