Acid-Base Balance
Conditions
Keywords
Venous blood gas, Arterial blood gas, pH, pCO2, Bicarbonate
Brief summary
The purpose of this study is to examine the agreement between venous blood gas and arterial blood gas measurements in patients in the Intensive Care Unit.
Detailed description
Venous blood gas analysis may be an alternative to arterial blood gas analysis for acid-base status, reducing the need for frequent invasive arterial sampling. The objective of this study is to examine the agreement between ABG and VBG samples for all commonly used parameters (pH, pCO2 and bicarbonate) in a pathologically diverse ICU patient population, specifically analyzing multiple paired arterial and venous samples from each patient.
Interventions
PROCEDUREVenous blood gas analysis
When an ABG is deemed to be necessary as part of ICU management, a central venous sample will also be obtained with minimum delay (always \< 2 minutes) between the samples. The samples will be analyzed by a blood gas analyzer as quickly as possible.
Sponsors
Olive View-UCLA Education & Research Institute
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adult patients 18 years or older * Admitted to the Intensive Care Unit (ICU) * Determined by their treating clinicians to require both a central venous line and arterial line
Exclusion criteria
* None
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Agreement between venous and arterial blood gas measurements of pH, pCO2 and bicarbonate | Duration of Intensive Care Unit Admission |
Outcome results
None listed