Recurrence of Febrile Seizure
Conditions
Brief summary
We wanted to find out if the early use of antipyretics is capable in preventing recurrences of febrile seizures. When a child has had his/her first febrile seizure, the parents were instructed to give him/her antipyretic medication every time when the child had a new episode of fever during two years.
Interventions
DRUGDiclofenac, Paracetamol, Ibuprofen
Immediately if temperature \> 38 degree Celsius, diclofenac suppository 1,5 mg/kg once or placebo suppository After eight hours, if temperature still \< 38 degree Celsius, acetaminophen mixture 15 mg/kg up to four times a day, or ibuprofen mixture 10 mg/kg up to four times a day, or placebo mixture up to four times a day as long as temperature \< 38 degree Celsius
Sponsors
University of Oulu
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
3 Months to 4 Years
Healthy volunteers
No
Inclusion criteria
* First febrile convulsion
Exclusion criteria
* Any prior convulsion or antiepileptic medication
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| recurrence of febrile seizure | two years |
Secondary
| Measure | Time frame |
|---|---|
| we only had the primary outcome measure | two years |
Countries
Finland
Outcome results
None listed