The Influence of Intensive Education and Coaching on Compliance for Oral Ganciclovir in the Prophylaxis of CMV: an Open Randomised Trial

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00566072

Enrollment

Registered

2007-12-03

Start date

2001-05-31

Completion date

2003-05-31

Last updated

2007-12-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cytomegalovirus Infections

Keywords

the effect of information on compliance of medication

Brief summary

21 patients were randomised to receive instructions and coaching or no intervention on the use and intake of ganciclovir. Intake of medication was measured by an electronic pill box. The duration of the study was 100 days.

Interventions

BEHAVIORALinstructions and coaching

instructions and coaching or no intervention on the use and intake of ganciclovir

Study design

Allocation

RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

SUPPORTIVE_CARE

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

* men and women between 18 and 65 years old * de novo kidney transplant patients * patients who need CMV prophylaxis with ganciclovir during 3 months * patients who gave informed consent after an oral explanation of the study

Exclusion criteria

* patients who are seronegative for CMV virus and who received a kidney from a CMV negative donor * patients with a creatinin clearance of less than 10 ml/min

Design outcomes

Primary

Measure	Time frame
relation between compliance of medication towards chemoprophylaxis and occurrence of CMV infection after kidney transplantation	weekly follow-up

Secondary

Measure	Time frame
relation between compliance and the instructions which a patient gets about intake of medication	weekly follow-up

Countries

Belgium

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026