RCT of the Efficacy of the Ketogenic Diet in the Treatment of Epilepsy

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00564915

Enrollment

145

Registered

2007-11-29

Start date

2001-12-31

Completion date

2006-07-31

Last updated

2007-11-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Epilepsy

Keywords

Epilepsy

Brief summary

A study of the efficacy and tolerability of two different ketogenic diets in children with drug resistant epilepsy; children resistant to at least two drugs randomised to reveive diet after baseline or after further 3m control period; in addition randomised to either MCT or classical ketogenic diet.

Interventions

DIETARY_SUPPLEMENTKetogenic diet

Ketogenic diet

Study design

Allocation

RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

2 Years to 16 Years

Healthy volunteers

Inclusion criteria

* Diagnosis of epilepsy for at least 2 years, resistant to at least two AEDs, at least 7 seizures/week

Design outcomes

Primary

Measure	Time frame
Change in seizure frequency	3 months

Secondary

Measure	Time frame
Tolerability and assessment of ketosis and growth	3 months

Countries

United Kingdom

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Apr 5, 2026