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Change of Neural Network Indicators Through Narrative Treatment of PTSD in Torture Victims

Change of Neural Network Indicators Through Narrative Treatment of PTSD in Torture Victims

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00563888
Enrollment
30
Registered
2007-11-26
Start date
2007-01-31
Completion date
2008-12-31
Last updated
2007-11-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

PTSD

Keywords

PTSD, torture survivors, Narrative Exposure Therapy, trauma-related memory processes, steady state visual evoked fields

Brief summary

Effective Treatment of PTSD involves talking about the traumatic event in detail.It is unclear how this process influences the sensory-specific trauma network (fear structure)in the traumatized person. The goal of the project is to test the hypothesis that treatment-facilitated recovery does not change the original fear structure but establishes an inhibitory mechanism that depends on verbal activity. An affective visual steady-state paradigm in magnetencephalography (MEG) using positive, aversive and neutral picture stimuli will be used to examine the spatial and temporal pattern of the processing of emotional stimuli. To examine the effects of treatment this paradigm will be used as outcome measure within a randomized controlled trial of Narrative Exposure Therapy and a waiting-list control condition for severely traumatized torture victims.

Interventions

BEHAVIORALNET

Narrative Exposure Therapy for traumatized survivors of organized violence

Sponsors

German Research Foundation
CollaboratorOTHER
University of Konstanz
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* experiences of organized violence/torture * PTSD diagnosis

Exclusion criteria

* psychotic disorder * neurological disease or seizures * current drug/alcohol abuse

Design outcomes

Primary

MeasureTime frame
PTSD diagnosis and severity score according to the Clinicians Administered PTSD Scale (CAPS)4 & 9 months after completion of treatment

Secondary

MeasureTime frame
steady state visual evoked magnetic fields in response to affective stimuli4 & 9 months after completion of treatment

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 27, 2026