Effects on Glutamine on the Outcome of Allogeneic Bone Marrow Transplant Recipients

A Randomized Control Studies on the Effects of Glutamine on the Clinical Outcome of Bone Marrow Transplant Recipients With Special Reference to Veno-occlusive Disease and Mucositis.

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00563498

Enrollment

Registered

2007-11-26

Start date

2004-07-31

Completion date

2006-06-30

Last updated

2010-07-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatic Veno-Occlusive Disease, Mucositis, Pulmonary Veno-Occlusive Disease

Keywords

Veno-occlusive disease, Mucositis

Brief summary

The primary purpose of this project is to investigate if addition of glutamine, an amino acid, to standard parenteral nutrition, may improve the clinical outcome of the bone marrrow transplantation reducing the occurrence of veno-occlusive disease and severity of mucositis.

Interventions

DRUGGlutamine

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

DOUBLE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Inclusion criteria

* Allogeneic bone marrow transplant recipients using busulfan and cyclophosphamide as conditioning.

Design outcomes

Primary

Measure	Time frame
Veno-occlusive disease	1 month
Mucositis	1 month

Secondary

Measure	Time frame
Hospital stay	2 months
Use of antibiotics	2 months

Countries

China

Contacts

Primary ContactYH Leung, Dr

ayhleung@hku.hk(852) 2855 3347

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026